She is also a descendant of Samson Occom, the 18th-century Mohegan scholar and minister whose fundraising efforts helped found the school that became Dartmouth.
After majoring in Native American studies at Dartmouth and earning a JD from American University Washington College of Law, Harris practiced law in Washington, D.C., representing Native American tribes and tribal entities and organizations. In 2010, she was appointed special assistant to the solicitor of the U.S. Department of the Interior and went on to serve as chief of staff to the assistant secretary of Indian Affairs, working on policy issues related to tribal sovereignty. She was elected to the Mohegan Tribal Council in 2017 and became vice chairwoman in 2019.
Harris is also a member of the U.S. Department of Justice's Tribal Nations Leadership Council.
In 2022, her efforts as a member of Dartmouth's Native American Visiting Committee helped bring about the repatriation of Samson Occom's papers to the Mohegan Tribe, a story recounted in the award-winning 2026 documentary Forgotten Founder: The Untold Story of Samson Occom and Dartmouth—a co-production of the Mohegan Tribe and Dartmouth in which Harris appears prominently.
The secretary of the United South and Eastern Tribes Sovereignty Protection Fund, she was a 2016 recipient of the National Center for American Indian Enterprise Development's "Native American 40 Under 40" award. Harris and her husband, Matt, are the parents of twins, Madeline and Jase.